Abstract
Veech reviews ketone bodies — β-hydroxybutyrate and partners — as alternative fuel and redox modifiers with therapeutic angles in ketosis and pathology.
Veech, R. L. (2004). Prostaglandins, Leukotrienes and Essential Fatty Acids, 70(3), 309–319. DOI
Key findings
- Alternative fuel — Ketones substitute for glucose in brain and heart under carbohydrate restriction.
- Redox effects — Ketone metabolism shifts NADH/NAD+ balance — signalling, not only calories.
- Therapeutic angles — Ketosis discussed for epilepsy, neurodegeneration, metabolic stress — mechanism-first.
- Pathology caveats — Benefits depend on condition and context — not universal keto endorsement.
Limits
Mechanistic review — not individual medical prescription.
Application
When you explore ketosis — ketones act as fuel and signalling, not only calorie subtraction. See Ketosis.