Abstract
Bliss and Lømo report long-term potentiation — repeated stimulation strengthens synaptic transmission — a cellular substrate for learning and memory.
Bliss, T. V., & Lomo, T. (1973). Nature, 243, 334–336. DOI
Key findings
- LTP discovery — High-frequency stimulation potentiates synapses for hours — activity leaves a lasting trace.
- Hebbian substrate — LTP became the leading cells-that-fire-together mechanism for memory research.